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Article

Better safe than sorry-Whole-genome sequencing indicates that missense variants are significant in susceptibility to COVID-19.

PloS one - 1 Jan 2023

Słomian Dawid, Szyda Joanna, Dobosz Paula, Stojak Joanna, Michalska-Foryszewska Anna, Sypniewski Mateusz, Liu Jakub, Kotlarz Krzysztof, Suchocki Tomasz, Mroczek Magdalena, Stępień Maria, Sztromwasser Paweł, Król Zbigniew J

Abstract excerpt

Undoubtedly, genetic factors play an important role in susceptibility and resistance to COVID-19. In this study, we conducted the GWAS analysis. Out of 15,489,173 SNPs, we identified 18,191 significant SNPs for severe and 11,799 SNPs for resistant phenotype, showing that a great number of loci were significant in different COVID-19 representations. The majority of variants were synonymous (60.56% for severe,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36662838
DOI: 10.1371/journal.pone.0279356
PMCID: PMC9858061

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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