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Article

MN1 altered astroblastoma with APC and LRP1B gene mutations: a unique variant in the cervical spine of a pediatric patient.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 May 2023

Mugge Luke, Dang Danielle D, Stabingas Kristen, Keating Gregory, Rossi Christopher, Keating Robert

Abstract excerpt

PURPOSE: Astroblastomas (AB) are high-grade neoplasms which typically occur within the cerebral hemisphere. However, given the rarity of this neoplasm and the number of variants, the relevance of this molecular makeup is unknown. We sought to describe the clinical presentation, treatment, and pathological analysis of a novel MN1 (meningioma 1) cervical spinal cord astroblastoma variant presenting in a pediatric...

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PMID: 36648513
DOI: 10.1007/s00381-022-05795-y

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