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Flavivirus prM interacts with MDA5 and MAVS to inhibit RLR antiviral signaling

13 Jan 2023

Abstract excerpt

BACKGROUND: Vector-borne flaviviruses, including tick-borne encephalitis virus (TBEV), Zika virus (ZIKV), West Nile virus (WNV), yellow fever virus (YFV), dengue virus (DENV), and Japanese encephalitis virus (JEV), pose a growing threat to public health worldwide, and have evolved complex mechanisms to overcome host antiviral innate immunity. However, the underlying mechanisms of flavivirus structural proteins to...

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PMID: 36639652
DOI: 10.1186/s13578-023-00957-0

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