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The structural protein VP3 of enterovirus D68 interacts with MAVS to inhibit the NF-κB signaling pathway

5 Mar 2025

Abstract excerpt

Enterovirus D68 (EV-D68) is an emerging pathogen causing severe respiratory infections, and the immune evasion mediated by EV-D68 structural protein has been under discussion for several years. Our early research has identified that EV-D68 structural protein VP3 targets specifically the interferon regulatory factor 7 to inhibit type I interferon signaling, but not interferon regulatory factor 3, which is...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 40042308
DOI: 10.1128/jvi.00163-25

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