Dengue Virus 2 NS2B Targets MAVS and IKKε to Evade the Antiviral Innate Immune Response

Abstract excerpt

Dengue viruses, members of the family Flaviviridae, can be spread to humans from mosquitos. DENVs consist of four popularly known serotypes (DENV1-4) and cause about 390 million people to be infected each year globally, of which 96 million cases are clinically manifested DENV infection results in a variety of diseases, ranging from mild fever to severe syndromes, such as dengue hemorrhagic fever and dengue shock...

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