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Article

Cross-Trait Mendelian Randomization Study to Investigate Whether Migraine Is a Risk Factor for Multiple Sclerosis.

Neurology - 28 Mar 2023

Horton Mary K, Robinson Sarah C, Shao Xiaorong, Quach Hong, Quach Diana, Choudhary Vidhu, Bellesis Kalliope H, Dorin Pete, Mei Jin, Chinn Terrence, Meyers Travis J, Bakshi Nandini, Marcus Jacqueline F, Waubant Emmanuelle, Schaefer Catherine A, Barcellos Lisa F

Abstract excerpt

BACKGROUND AND OBJECTIVES: Migraine is common among people with multiple sclerosis (MS), but the reasons for this are unknown. We tested 3 hypothesized mechanisms for this observed comorbidity, including migraine is a risk factor of MS, genetic variants are shared between the conditions, and migraine is because of MS. METHODS: Data were from 2 sources: publicly available summary statistics from genome-wide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36631270
DOI: 10.1212/WNL.0000000000206791
PMCID: PMC10065202

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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