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Article

Capecitabine-induced hand-foot syndrome: A pharmacogenetic study beyond DPYD

9 Jan 2023

Abstract excerpt

AIM OF THE STUDY: Occurrence of hand-foot syndrome (HFS) during capecitabine treatment often results in treatment interruptions (26 %) or treatment discontinuation (17 %), and can severely decrease quality of life. In this study, we investigated whether single nucleotide polymorphisms (SNPs) in genes involved in capecitabine metabolism - other than DPYD - are associated with an increased risk for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36630849
DOI: 10.1016/j.biopha.2023.114232

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