Article
[Efficacy of Osimertinib Combined with Bevacizumab in Advanced Non-small Cell Lung Cancer Patients with Acquired EGFR T790M Mutation].
Zhongguo fei ai za zhi = Chinese journal of lung cancer - 20 Dec 2022
Gu Yanfei, Tian Xiaoru, Wang Ruotian, Li Xiaoxue, Qian Kun, Li Yuanbo, Nong Jingying
Abstract excerpt
BACKGROUND: Osimertinib is a third-generation epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) capable of overcoming non-small cell lung cancer (NSCLC) with EGFR T790M mutation. Although the addition of bevacizumab to 1st generation EGFR-TKIs confers a significant improvement in progression-free survival (PFS) in treatment-naive EGFR mutant NSCLC patients, osimertinib plus bevacizumab...
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