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Article

Canine Model of Human Frailty: Adaptation of a Frailty Phenotype in Older Dogs.

The journals of gerontology. Series A, Biological sciences and medical sciences - 2 Aug 2023

Lemaréchal Romane, Hoummady Sara, Barthélémy Inès, Muller Claude, Hua Julie, Gilbert Caroline, Desquilbet Loïc

Abstract excerpt

Frailty is a clinical presentation resulting from age-related cumulative declines in several physiological systems. The aim of this study was to adapt the concept of frailty to the domestic dog, as a model for frailty research, by characterizing a 5-criterion frailty phenotype using objective measurement, and to investigate its independent association with death. A prospective cohort including 80 Labrador and...

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Identifiers

PMID: 36617213
DOI: 10.1093/gerona/glad006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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