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PHF5A facilitates the development and progression of gastric cancer through SKP2-mediated stabilization of FOS

6 Jan 2023

Abstract excerpt

BACKGROUND: Gastric cancer (GC) is the fifth most common cancer and the third most common cause of cancer death worldwide. Plant homeodomain (PHD)-finger domain protein PHF5A has been demonstrated to play a promoting role in a variety of cancers. This study aimed to clarify the role of PHF5A in the progression of GC and its potential mechanism of action. METHODS: Immunohistochemical staining experiments were...

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PMID: 36609277
DOI: 10.1186/s12967-022-03821-w

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