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Article

Identification of circular RNAs hosted by the RPGR ORF15 genomic locus.

RNA biology - 1 Jan 2023

Appelbaum Tatyana, Aguirre Gustavo D, Beltran William A

Abstract excerpt

Mutations in the retina-specific isoform of the gene encoding retinitis pigmentosa GTPase regulator (RPGRorf15) cause X-linked retinitis pigmentosa, a severe and early onset inherited retinal degeneration. The underlying pathogenic mechanisms and variability in disease severity remain to be fully elucidated. The present study examines structural features of the ORF15 exonic region to provide new insights into the...

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Identifiers

PMID: 36593651
DOI: 10.1080/15476286.2022.2159165
PMCID: PMC9817113

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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