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Article

Paternal inheritance predicts earlier cardiovascular event onset in patients with familial hypercholesterolemia.

Atherosclerosis - 1 Jul 2021

Paquette Martine, Fantino Manon, Bernard Sophie, Baass Alexis

Abstract excerpt

BACKGROUND AND AIMS: Familial hypercholesterolemia (FH) is a genetic disease, with an autosomal codominant inheritance, predisposing to premature atherosclerotic cardiovascular disease (ASCVD). Paternal or maternal inheritance of the FH-causing mutation may affect the FH phenotype in offspring, but the effect of the genetic transmission on cardiovascular disease risk remains to be established. The aim of the...

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Identifiers

PMID: 34157652
DOI: 10.1016/j.atherosclerosis.2021.06.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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