Article
[Localization of active sites in human ceruloplasmin from data of intra- and intermolecular homology].
Molekuliarnaia biologiia - 1 Jan 2000
Moshkov K A, Vagin A A, Zaĭtsev V N
Abstract excerpt
The identification of possible copper ligands in human ceruloplasmin was carried out by the computer similarity analysis for sequences of ceruloplasmin and several other copper oxidases: azurin, plastocyanin, superoxide dismutase, tyrosinase and hemocyanin. It follows from the analysis of inter- and intramolecular homology that copper active sites of different types appeared to be in close contacts within the...
Topics
- Amino Acid Sequence
- Binding Sites
- Ceruloplasmin
- Copper
- Humans
- Ligands
- Metalloproteins
- Mutation