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Mitochondrial function of human embryo: Decline in their quality with maternal aging

1 Jan 2022

Abstract excerpt

Background: Female fertility declines with age, due to increased chromosomal aneuploidy and possible reduced mitochondrial function in the embryo. Methods: This review outlines how mitochondrial function in human embryos, as predicted from oxygen consumption rate (OCR) measurements, changes in preimplantation stage, and what factors, particularly maternal age, affect mitochondrial function in embryos. Main...

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PMID: 36570768
DOI: 10.1002/rmb2.12491

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