Article
Bayesian Molecular Dating Analyses Combined with Mutational Profiling Suggest an Independent Origin and Evolution of SARS-CoV-2 Omicron BA.1 and BA.2 Sub-Lineages.
Viruses - 12 Dec 2022
Kumar Naveen, Kaushik Rahul, Singh Ashutosh, Uversky Vladimir N, Zhang Kam Y J, Sahu Upasana, Bhatia Sandeep, Sanyal Aniket
Abstract excerpt
The ongoing evolution of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) has resulted in the recent emergence of a highly divergent variant of concern (VOC) defined as Omicron or B.1.1.529. This VOC is of particular concern because it has the potential to evade most therapeutic antibodies and has undergone a sustained genetic evolution, resulting in the emergence of five distinct sub-lineages....
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