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Alphavirus Particles Can Assemble with an Alternate Triangulation Number

27 Nov 2022

Abstract excerpt

Alphaviruses are spherical, enveloped RNA viruses primarily transmitted by mosquitoes, and cause significant arthritogenic and neurotropic disease in humans and livestock. Previous reports have shown that—in contrast to prototypical icosahedral viruses—alphaviruses incorporate frequent defects, and these may serve important functions in the viral life cycle. We confirm the genus-wide pleomorphism in live viral...

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PMID: 36560655
DOI: 10.3390/v14122650

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