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Evolution of SARS-CoV-2: BA.4/BA.5 Variants Continues to Pose New Challenges

23 Nov 2022

Abstract excerpt

The acquisition of a high number of mutations, notably, the gain of two mutations L452R and F486V in RBD, and the ability to evade vaccine/natural infection-induced immunity suggests that Omicron is continuing to use "immune-escape potential" as an evolutionary space to maintain a selection advantage within the population. Despite the low hospitalizations and lower death rate, the surges by these variants may...

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PMID: 36560614
DOI: 10.3390/v14122610

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