Article
Assessment of the Frequency, Phenotypes, and Outcomes of Acute Liver Injury Associated with Amoxicillin/Clavulanate in 1.4 Million Patients in the Veterans Health Administration.
Drug safety - 1 Feb 2023
Suzuki Ayako, Tillmann Hans, Williams James, Hauser Ronald G, Frund Julie, Suzuki Mizuki, Prior Fred, Aithal Guruprasad P, Lucena M Isabel, Andrade Raúl J, Tong Weida, Hunt Christine M
Abstract excerpt
INTRODUCTION: Drug-induced liver injury is a significant health issue, yet the exposure-based incidence remains to be characterized. OBJECTIVE: We aimed to assess the frequency, phenotypes, and outcomes of acute liver injury associated with amoxicillin/clavulanate using a large electronic health record system. METHODS: Using the Veterans Health Administration electronic health record system, we developed the...
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