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Aztreonam-avibactam: an option against carbapenem-resistant Enterobacterales with emerging resistance

19 Oct 2022

Abstract excerpt

Dear Editor, The Enterobacterales are an order of Gram-negative bacteria comprising a few major human pathogens such as Escherichia coli and Klebsiella pneumoniae. However, carbapenem-resistant Enterobacterales (CRE) has risen as an urgent threat for human health, leading to high mortality with very limited antimicrobial options. The main mechanism mediating resistance to β-lactams including carbapenems in the...

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PMID: 36519138
DOI: 10.1093/pcmedi/pbac029

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