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Intracellular Transposition of Mobile Genetic Elements Associated with the Colistin Resistance Gene mcr-1

13 Dec 2022

Abstract excerpt

By analyzing the intracellular transfer of clinically relevant transposons, we can understand the dissemination and evolution of drug resistance conferring mobile genetic elements (MGEs) once a plasmid enters a cell following conjugation. This knowledge will help further our understanding of how these important genes move through bacterial populations. Utilizing the pBACpAK entrapment vector has allowed us to...

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PMID: 36511714
DOI: 10.1128/spectrum.03278-22

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