Article
High frequency of KRAS and EGFR mutation profiles in BRAF-negative thyroid carcinomas in Indonesia.
BMC research notes - 12 Dec 2022
Heriyanto Didik Setyo, Laiman Vincent, Limantara Nikko Vanda, Anantawikrama Widyan Putra, Yuliani Fara Silvia, Cempaka Rita, Anwar Sumadi Lukman
Abstract excerpt
OBJECTIVE: Thyroid cancer incidence has steadily increased in Indonesia. However, data on Kirsten rat sarcoma virus (KRAS) and EGFR mutations in thyroid cancer in Indonesia remain unavailable, except for BRAF-V600E, the most common BRAF gene mutation. This study aimed to analyze KRAS and EGFR mutation profiles in BRAF-V600E negative thyroid cancer samples. RESULTS: BRAF-V600E mutations were found in papillary...
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