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Mutation Profile of Well-Differentiated Thyroid Cancer in Asians

1 Jan 2015

Abstract excerpt

Recent advances in molecular diagnostics have led to significant insights into the genetic basis of thyroid tumorigenesis. Among the mutations commonly seen in thyroid cancers, the vast majority are associated with the mitogen-activated protein kinase pathway. B-Raf proto-oncogene (BRAF) mutations are the most common mutations observed in papillary thyroid cancers (PTCs), followed by RET/PTC rearrangements and...

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PMID: 26435130
DOI: 10.3803/enm.2015.30.3.252

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