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Article

Parental Genetics Communicate with Intrauterine Environment to Reprogram Newborn Telomeres and Immunity.

Cells - 25 Nov 2022

Farrukh Sadia, Baig Saeeda, Hussain Rubina, Imad Rehan, Khalid Maria

Abstract excerpt

Telomeres, markers for cellular senescence, have been found substantially influenced by parental inheritance. It is well known that genomic stability is preserved by the DNA repair mechanism through telomerase. This study aimed to determine the association between parents−newborn telomere length (TL) and telomerase gene (TERT), highlighting DNA repair combined with TL/TERT polymorphism and immunosenescence of the...

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Identifiers

PMID: 36497039
DOI: 10.3390/cells11233777
PMCID: PMC9735452

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