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Comprehensive research on the distribution of HLA-DRB1 in Chinese populations.

HLA - 1 Mar 2023

Fan Baitong, Huang Xiaoqin, Zhang Xiaochao, Huang Lifan, Yang Zhaoqing, Ma Shaohui, Chu Jiayou, Huang Kai, Weng Yuting, Zhang Lin, Lin Keqin, Sun Hao

Abstract excerpt

By presenting antigen peptides, HLA-DRB1 plays an important role in the immune system. However, the allele frequency of HLA-DRB1 exon 2 across China has not been comprehensively studied, especially in minority populations. We sampled 3757 individuals from 59 population. The HLA-DRB1 region from 212 to 463 bp (NM_002124.4 exon 2) in each population was sequenced by Sanger sequencing and genotyped via SBTengine®...

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PMID: 36479840
DOI: 10.1111/tan.14923

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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