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A transcriptional switch controls sex determination in Plasmodium falciparum

7 Dec 2022

Abstract excerpt

Abstract Sexual reproduction and meiotic sex are deeply rooted in the eukaryotic tree of life, but mechanisms determining sex or mating types are extremely varied and are only well characterized in a few model organisms 1 . In malaria parasites, sexual reproduction coincides with transmission to the vector host. Sex determination is non-genetic, with each haploid parasite capable of producing either a male or a...

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PMID: 36477538
DOI: 10.1038/s41586-022-05509-z

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