Article
Mutation in a chlorophyll-binding motif of Brassica ferrochelatase enhances both heme and chlorophyll biosynthesis.
Cell reports - 6 Dec 2022
Liu Mengyang, Ma Wei, Su Xiangjie, Zhang Xiaomeng, Lu Yin, Zhang Shaowei, Yan Jinghui, Feng Daling, Ma Lisong, Taylor Aoife, Ge Yunjia, Cheng Qi, Xu Kedong, Wang Yanhua, Li Na, Gu Aixia, Zhang Ju, Luo Shuangxia, Xuan Shuxin, Chen Xueping, Scrutton Nigel S, Li Chengwei, Zhao Jianjun, Shen Shuxing
Abstract excerpt
The heme branch of tetrapyrrole biosynthesis contributes to the regulation of chlorophyll levels. However, the mechanism underlying the balance between chlorophyll and heme synthesis remains elusive. Here, we identify a dark green leaf mutant, dg, from an ethyl methanesulfonate (EMS)-induced mutant library of Chinese cabbage. The dg phenotype is caused by an amino acid substitution in the conserved chlorophyll...
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