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Saliva‐based cell‐free DNA and cell‐free mitochondrial DNA in head and neck cancers have promising screening and early detection role

2 Dec 2022

Abstract excerpt

BACKGROUND: Cell-free DNA (cfDNA) and cell-free mitochondrial DNA (cf-mtDNA) have been postulated as potential diagnostic and prognostic biomarkers for different human malignancies. Early detection of head and neck malignancies is fundamental for optimal patient management. This study, therefore, aimed to assess the utility of saliva-based liquid biopsy as a noninvasive source of cfDNA and cf-mtDNA for detecting...

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PMID: 36459078
DOI: 10.1111/jop.13392

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