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Article

Congenital hypothyroidism and thyroid cancer.

Endocrine-related cancer - 1 Sept 2021

Penna Gustavo, Rubio Ileana G S, Brust Ester Saraiva, Cazarin Juliana, Hecht Fabio, Alkmim Nina Ramalho, Rajão Kamilla M A Brandão, Ramos Helton Estrela

Abstract excerpt

Differentiated thyroid carcinoma (DTC) combined with congenital hypothyroidism (CH) is a rare situation, and there is no well-established causal relationship. CH is a common congenital endocrine, while DTC occurring in childhood represents 0.4-3% of all malignancies at this stage of life. The association of CH with DTC could be related to dyshormonogenetic goiter (DHG) or developmental abnormalities. This review...

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PMID: 34378152
DOI: 10.1530/ERC-21-0159

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