Article
Mutation analysis performed on tumor biopsies from patients with newly-diagnosed germinal center aggressive B cell lymphomas.
Oncotarget - 17 Nov 2022
Landsburg Daniel J, Morrissette Jennifer J D, Schuster Stephen J, Nasta Sunita D, Gerson James N, Barta Stefan K, Svoboda Jakub, Chong Elise A, Lim Megan S
Abstract excerpt
Comprehensive genomic analyses of tumor biopsies from patients with newly-diagnosed germinal center B cell (GCB) diffuse large B cell/high grade B cell lymphoma (DLBCL/HGBL) have identified molecular subtypes predictive of inferior survival, which are characterized by somatic mutations that can be detected through clinical laboratory mutation analysis (CLMA). To determine the frequency and predictive value of...
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