Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HNRNPK/CLCN3 axis facilitates the progression of LUAD through CAF-tumor interaction

1 Jan 2022

Abstract excerpt

Background: Chloride channel 3 (CLCN3) is regulated by transcription-coactivator, however, it is unclear which core transcription factor regulates CLCN3. The role of CLCN3 in lung adenocarcinoma (LUAD) is unexplored and the relationship between CLCN3 and tumor microenvironment is unknown. Methods: A 5-biotin-labeled promoter probe of CLCN3 was used to pull down the promoter-binding transcription factor. Further...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Ferroptosis and cancer prognosis
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36439880
DOI: 10.7150/ijbs.76083

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HNRNPK/CLCN3 axis facilitates the progression of LUAD through CAF-tumor interactionPMID 36439880Read ↗

CNGA3, a Protective Ion Channel Gene, Is Highly Expressed in Lung Adenocarcinoma and Predicts a Favorable PrognosisSemantic proximity Read ↗

miR-1-3p/CELSR3 Participates in Regulating Malignant Phenotypes of Lung Adenocarcinoma Cells.Semantic proximity Read ↗

COL3A1‐positive endothelial cells influence LUAD prognosis and regulate LUAD carcinogenesis by NCL–PI3K–AKT axisSemantic proximity Read ↗

lncITPF Promotes Pulmonary Fibrosis by Targeting hnRNP-L Depending on Its Host Gene ITGBL1Semantic proximity Read ↗

POU2AF2/C11orf53 functions as a co-activator of POU2F3 by maintaining chromatin accessibility and enhancer activitySemantic proximity Read ↗

Pan-cancer analysis reveals the prognostic relevance of NUP54 and its association with HIF-1α-related glycolytic phenotypes in lung adenocarcinoma.Semantic proximity Read ↗

LUAD BALF Exosomal miR-183-5p promoted the metastasis of NLCSCSemantic proximity Read ↗

LncRNA MANCR positively affects the malignant progression of lung adenocarcinomaSemantic proximity Read ↗

Akt kinase LANCL2 functions as a key driver in EGFR-mutant lung adenocarcinoma tumorigenesis.Semantic proximity Read ↗

LINC00346 Sponges miR-30c-2-3p to Promote the Development of Lung Adenocarcinoma by Targeting MYBL2 and Regulating CELL CYCLE Signaling PathwaySemantic proximity Read ↗

hnRNPK-regulated LINC00263 promotes malignant phenotypes through miR-147a/CAPN2.Semantic proximity Read ↗

CircBCAR3 accelerates esophageal cancer tumorigenesis and metastasis via sponging miR-27a-3pSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.