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Article

Pan-cancer analysis reveals the prognostic relevance of NUP54 and its association with HIF-1α-related glycolytic phenotypes in lung adenocarcinoma.

Cellular signalling - 1 Oct 2026

Cheng Peng, Song Chengru, Han Qian, Yang Hongjie, Fan Ruitai

Abstract excerpt

The role of the nuclear pore protein NUP54 in tumorigenesis and progression remains unclear. By integrating multiomics data from TCGA, GTEx, CPTAC, and other sources, in this study, the first pan-cancer landscape of NUP54 was systematically delineated: its mRNA and protein expression levels are significantly upregulated in most types of cancer, including lung adenocarcinoma, hepatocellular carcinoma, and gastric...

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Share to Adenocarcinoma of Lung
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Proliferation

Share to Gene Expression Regulation, Neoplastic

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Share to Hypoxia-Inducible Factor 1, alpha Subunit

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Source

Identifiers

PMID: 42349706
DOI: 10.1016/j.cellsig.2026.112697

Genes

NUP54
LDHA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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