Article
Detection of potential functional variants based on systems-biology: the case of feed efficiency in beef cattle.
BMC genomics - 25 Nov 2022
Ribeiro Gabriela, Baldi Fernando, Cesar Aline S M, Alexandre Pâmela A, Peripolli Elisa, Ferraz José B S, Fukumasu Heidge
Abstract excerpt
BACKGROUND: Potential functional variants (PFVs) can be defined as genetic variants responsible for a given phenotype. Ultimately, these are the best DNA markers for animal breeding and selection, especially for polygenic and complex phenotypes. Herein, we described the identification of PFVs for complex phenotypes (in this case, Feed Efficiency in beef cattle) using a systems-biology driven approach based on...
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