Article
Development and comparison of RNA-sequencing pipelines for more accurate SNP identification: practical example of functional SNP detection associated with feed efficiency in Nellore beef cattle.
BMC genomics - 8 Oct 2020
Lam S, Zeidan J, Miglior F, Suárez-Vega A, Gómez-Redondo I, Fonseca P A S, Guan L L, Waters S, Cánovas A
Abstract excerpt
BACKGROUND: Optimization of an RNA-Sequencing (RNA-Seq) pipeline is critical to maximize power and accuracy to identify genetic variants, including SNPs, which may serve as genetic markers to select for feed efficiency, leading to economic benefits for beef production. This study used RNA-Seq data (GEO Accession ID: PRJEB7696 and PRJEB15314) from muscle and liver tissue, respectively, from 12 Nellore beef steers...
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