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Article

Immune phenotypes that are associated with subsequent COVID-19 severity inferred from post-recovery samples.

Nature communications - 25 Nov 2022

Liechti Thomas, Iftikhar Yaser, Mangino Massimo, Beddall Margaret, Goss Charles W, O'Halloran Jane A, Mudd Philip A, Roederer Mario

Abstract excerpt

Severe COVID-19 causes profound immune perturbations, but pre-infection immune signatures contributing to severe COVID-19 remain unknown. Genome-wide association studies (GWAS) identified strong associations between severe disease and several chemokine receptors and molecules from the type I interferon pathway. Here, we define immune signatures associated with severe COVID-19 using high-dimensional flow...

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Identifiers

PMID: 36433939
DOI: 10.1038/s41467-022-34638-2
PMCID: PMC9700777

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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