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A Novel TP53 Gene Mutation Sustains Non-Small Cell Lung Cancer through Mitophagy.

Cells - 13 Nov 2022

Wang Yuanli, Goh Kah Yong, Chen Zhencheng, Lee Wen Xing, Choy Sze Mun, Fong Jia Xin, Wong Yun Ka, Li Dongxia, Hu Fangrong, Tang Hong-Wen

Abstract excerpt

Lung cancer is the leading cause of cancer death in the world. In particular, non-small-cell lung cancer (NSCLC) represents the majority of the lung cancer population. Advances in DNA sequencing technologies have significantly contributed to revealing the roles, functions and mechanisms of gene mutations. However, the driver mutations that cause cancers and their pathologies remain to be explored. Here, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36429016
DOI: 10.3390/cells11223587
PMCID: PMC9688643

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