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Article

Whole exome sequencing identifies KIF26B, LIFR and LAMC1 mutations in familial vesicoureteral reflux.

PloS one - 1 Jan 2022

Bartik Zsuzsa I, Sillén Ulla, Djos Anna, Lindholm Anna, Fransson Susanne

Abstract excerpt

Vesicoureteral reflux (VUR) is a common urological problem in children and its hereditary nature is well recognised. However, despite decades of research, the aetiological factors are poorly understood and the genetic background has been elucidated in only a minority of cases. To explore the molecular aetiology of primary hereditary VUR, we performed whole-exome sequencing in 13 large families with at least three...

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PMID: 36417404
DOI: 10.1371/journal.pone.0277524
PMCID: PMC9683562

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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