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Article

Single-cell profiling reveals distinct immune phenotypes that contribute to ischaemia-reperfusion injury after steatotic liver transplantation.

Cell proliferation - 1 Oct 2021

Yang Xinyu, Lu Di, Wang Rui, Lian Zhengxing, Lin Zuyuan, Zhuo Jianyong, Chen Hao, Yang Modan, Tan Winyen, Yang Mengfan, Wei Xuyong, Wei Qiang, Zheng Shusen, Xu Xiao

Abstract excerpt

OBJECTIVES: The discrepancy between supply and demand of organ has led to an increased utilization of steatotic liver for liver transplantation (LT). Hepatic steatosis, however, is a major risk factor for graft failure due to increased susceptibility to ischaemia-reperfusion (I/R) injury during transplantation. MATERIALS AND METHODS: To assess the plasticity and phenotype of immune cells within the...

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Identifiers

PMID: 34469018
DOI: 10.1111/cpr.13116
PMCID: PMC8488562

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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