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Article

Functional imaging of mitochondria in genetically confirmed retinal dystrophies using flavoprotein fluorescence

2 Nov 2022

Abstract excerpt

Background Whether by indirect oxidative stress or direct genetic defect, various genetic retinal dystrophies involve mitochondrial stress. Mitochondrial flavoprotein fluorescence (FPF), reported as either average signal intensity or variability (heterogeneity), may serve as a direct, quantifiable marker of oxidative stress.Materials and Methods This observational study enrolled patients with genetically...

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PMID: 36384402
DOI: 10.1080/13816810.2022.2144903

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