Article
Association of MicroRNA Biogenesis Genes Polymorphisms with Risk of Large Artery Atherosclerosis Stroke.
Cellular and molecular neurobiology - 1 Aug 2022
Wang Mengmeng, Gu Jinyu, Shen Chong, Tang Wuzhuang, Xing Xiaoru, Zhang Zhizhong, Liu Xinfeng
Abstract excerpt
Convincing evidence has shown that microRNAs (miRNAs) are involved in the pathogenesis of stroke. This study aimed to examine whether miRNA biogenesis genes polymorphisms are associated with risk of large artery atherosclerosis (LAA) stroke. Three polymorphisms (DROSHA rs10719 T>C, RAN rs3803012 A>G, and PIWIL1 rs10773771 C>T) were screened by certain criteria. A total of 1,785 (710 cases and 1,075 controls)...
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