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Article

HtrA1 in Gestational Diabetes Mellitus: A Possible Biomarker?

5 Nov 2022

Abstract excerpt

BACKGROUND: The high-temperature requirement A 1 (HtrA1) is a multidomain secretory protein with serine-protease activity, expressed in many tissues, including placenta, where its expression is higher in the first trimester, suggesting an association of this serine protease in early phases of human placenta development. In this study, we evaluated maternal serum HtrA1 levels in the first and third trimester of...

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PMID: 36359548
DOI: 10.3390/diagnostics12112705

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