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Immunoengineered magnetic-quantum dot nanobead system for the isolation and detection of circulating tumor cells

23 Apr 2021

Abstract excerpt

BACKGROUND: Highly efficient capture and detection of circulating tumor cells (CTCs) remain elusive mainly because of their extremely low concentration in patients' peripheral blood. METHODS: We present an approach for the simultaneous capturing, isolation, and detection of CTCs using an immuno-fluorescent magnetic nanobead system (iFMNS) coated with a monoclonal anti-EpCAM antibody. RESULTS: The developed...

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PMID: 33892737
DOI: 10.1186/s12951-021-00860-1

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