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Article

[RFC1 CANVAS/Spectrum Disorder: Historical Details and Clinical Diversity].

Brain and nerve = Shinkei kenkyu no shinpo - 1 Nov 2022

Yoshida Kunihiro

Abstract excerpt

Cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS) refers to a multi-system neurodegenerative disorder, with middle-age onset, which mainly presents with progressive imbalance. Imbalance is attributable to isolated or combined impairment of the cerebellar, proprioceptive, and vestibular systems. Chronic spasmodic cough, which usually precedes neurological symptoms, serves as a useful...

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Identifiers

PMID: 36343927
DOI: 10.11477/mf.1416202222

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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[RFC1 CANVAS/Spectrum Disorder: Historical Details and Clinical Diversity].PMID 36343927Read ↗

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Cerebellar ataxia, neuropathy and vestibular areflexia syndrome (CANVAS): A family with five affected sibs from TurkeySemantic proximity Read ↗

Natural History, Phenotypic Spectrum, and Discriminative Features of Multisystemic RFC1 Disease.Semantic proximity Read ↗

Cramp-fasciculation syndrome phenotype of cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS) due to RFC1 repeat expansion.Semantic proximity Read ↗

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Frequency and phenotype of GAA-FGF14 disease in bilateral vestibulopathy syndromes: insights from repeat expansion carriers, including a case of co-occurrence with RFC1-related CANVAS.Semantic proximity Read ↗

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