Repeat expansions inRFC1gene in refractory chronic cough

Abstract excerpt

Introduction Refractory chronic cough (RCC), persisting despite addressing contributory diagnoses, is likely underpinned by neurally mediated cough hypersensitivity.RFC1disorders are genetic neurodegenerative conditions caused by biallelicRFC1repeat expansion sequences, commonly presenting with cough, followed by neurological features including cerebellar ataxia with neuropathy and vestibular areflexia syndrome...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Gastroesophageal reflux and treatments
• Share to Pediatric health and respiratory diseases
• Share to Respiratory and Cough-Related Research