Article
In situ, in vivo, and in vitro approaches for studying AMR plasmid conjugation in the gut microbiome
3 Nov 2022
Abstract excerpt
Antimicrobial resistance (AMR) is a global threat, with evolution and spread of resistance to frontline antibiotics outpacing the development of novel treatments. The spread of AMR is perpetuated by transfer of antimicrobial resistance genes (ARGs) between bacteria, notably those encoded by conjugative plasmids. The human gut microbiome is a known 'melting pot' for plasmid conjugation, with ARG transfer in this...
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