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Article

Roles for c-Abl in postoperative neurodegeneration

1 Jan 2022

Abstract excerpt

The nonreceptor tyrosine kinase c-Abl is inactive under normal conditions. Upon activation, c-Abl regulates signaling pathways related to cytoskeletal reorganization. It plays a vital role in modulating cell protrusion, cell migration, morphogenesis, adhesion, endocytosis and phagocytosis. A large number of studies have also found that abnormally activated c-Abl plays an important role in a variety of...

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PMID: 36313229
DOI: 10.7150/ijms.73740

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