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Article

Identifying and categorizing compounds that reduce corneal transforming growth factor beta induced protein levels: a scoping review.

Expert review of clinical pharmacology - 1 Dec 2022

Sciriha Gabriella Guo, Sultana Janet, Borg Joseph

Abstract excerpt

INTRODUCTION: Transforming growth factor beta induced (TGFBI) gene mutations have been reported as the cause of a group of genetically inherited, visually debilitating, corneal dystrophies (CD). A scoping literature review to identify and categorize compounds that inhibit corneal TGFBI expression and/or promote TGFBIp degradation was performed. Emphasis was given to their potential to be used as a cost-effective...

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Identifiers

PMID: 36308770
DOI: 10.1080/17512433.2022.2142560

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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