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Article

Molecular and Immunophenotypic Correlates of Metastatic Epithelioid Angiomyolipoma Include Alterations of TP53, RB1, and ATRX.

Archives of pathology & laboratory medicine - 1 Jul 2023

McCarthy Michael R, Nichols Paige E, Sharma Vidit, Stanton Melissa L, Reynolds Jordan P, Pitel Beth A, Halling Kevin C, Lohse Christine M, Herrera-Hernandez Loren, Thompson R Houston, Leibovich Bradley C, Jimenez Rafael E, Boorjian Stephen A, Cheville John C, Gupta Sounak

Abstract excerpt

CONTEXT.—: Epithelioid angiomyolipomas (eAMLs) are rare tumors of the kidney that occur in patients with tuberous sclerosis complex or in a sporadic setting; a subset of these tumors exhibit metastatic behavior. OBJECTIVE.—: To analyze molecular profiling data to identify pathogenic alterations in rare cases of metastatic eAML, and to identify immunohistochemistry (IHC)-based surrogate markers. DESIGN.—:...

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Identifiers

PMID: 36308711
DOI: 10.5858/arpa.2022-0127-OA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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