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Article

Immunohistochemistry of p53 and Ki-67 and p53 mutation analysis in renal epithelioid angiomyolipoma.

International journal of clinical and experimental pathology - 1 Jan 2015

Li Wenbin, Guo Lei, Bi Xingang, Ma Jianhui, Zheng Shan

Abstract excerpt

BACKGOUND: Renal epithelioid angiomyolipoma (EAML) is a rare variant of AML (angiomyolipoma) and is often associated with aggressive behaviors. The pathogenesis of EAML has been poorly understood. We analyzed the expression of p53 and Ki-67 by immunohistochemistry (IHC) and investigated p53 mutation analysis in 11 cases of EAML in comparison to classical AML. METHODS: P53 and Ki-67 expression status were...

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PMID: 26464702
PMCID: PMC4583934

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