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Genetic and Cross Neutralization Analyses of Coxsackievirus A16 Circulating in Taiwan from 1998 to 2021 Suggest Dominant Genotype B1 can Serve as Vaccine Candidate.

Viruses - 20 Oct 2022

Cheng Dayna, Chiu Yo-Wei, Huang Sheng-Wen, Lien Yun-Yin, Chang Chia-Lun, Tsai Huey-Pin, Wang Ya-Fang, Wang Jen-Ren

Abstract excerpt

Coxsackievirus A16 (CVA16) is well known for causing hand-foot-and-mouth disease (HFMD) and outbreaks were frequently reported in Taiwan in the past twenty years. The epidemiology and genetic variations of CVA16 in Taiwan from 1998 to 2021 were analyzed in this study. CVA16 infections usually occurred in early summer and early winter, and showed increased incidence in 1998, 2000-2003, 2005, 2007-2008, and 2010 in...

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Identifiers

PMID: 36298861
DOI: 10.3390/v14102306
PMCID: PMC9608817

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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