Article
Phenotypic and genomic characterization of human coxsackievirus A16 strains with distinct virulence in mice.
Virus research - 22 Jan 2014
Han Jian-Feng, Yu Nan, Pan Yu-Xian, He Si-Jie, Xu Li-Juan, Cao Rui-Yuan, Li Yue-Xiang, Zhu Shun-Ya, Zhang Yu, Qin E-De, Che Xiao-Yan, Qin Cheng-Feng
Abstract excerpt
Human coxsackievirus A16 (CA16) infection results in hand, foot, and mouth disease (HFMD) along with other severe neurological diseases in children and poses an important public health threat in Asian countries. During an HFMD epidemic in 2009 in Guangdong, China, two CA16 strains (GD09/119 and GD09/24) were isolated and characterized. Although both strains were similar in plaque morphology and growth properties...
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